D’Arcy, Pádraig: search on Z-Library

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1

Identification of Agents that Induce Apoptosis of Multicellular Tumour Spheroids: Enrichment for Mitotic Inhibitors with Hydrophobic Properties

Walid Fayad, Linda Rickardson, Caroline Haglund, Maria Hägg Olofsson, Padraig D’Arcy, Rolf Larsson, Stig Linder, Mårten Fryknäs

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 733 KB

english, 2011

2

Differential roles of SS18–SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth

Maria Törnkvist, Natalia Natalishvili, Yuntao Xie, Ada Girnita, Pádraig D’Arcy, Bertha Brodin, Magnus Axelson, Leonard Girnita

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 866 KB

english, 2008

3

Focal adhesion kinase (FAK) activates and stabilizes IGF-1 receptor

Sandra Andersson, Pádraig D’Arcy, Olle Larsson, Bita Sehat

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 498 KB

english, 2009

4

Reactivation of p53 function in synovial sarcoma cells by inhibition of p53–HDM2 interaction

Pádraig D’Arcy, Bríd Ann Ryan, Bertha Brodin

Journal:

Year:

2009

Language:

english

File:

PDF, 975 KB

english, 2009

5

The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy

Emma Hernlund, Maria Hägg Olofsson, Walid Fayad, Mårten Fryknäs, Karolina Lesiak-Mieczkowska, Xiaonan Zhang, Slavica Brnjic, Vivien Schmidt, Padraig D’Arcy, Tobias Sjöblom, Angelo De Milito, Rolf Lars

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

6

Activated monocytes augment TRAIL-mediated cytotoxicity by human NK cells through release of IFN-γ

Sarhan, Dhifaf, D'Arcy, Padraig, Wennerberg, Erik, Lidén, Majken, Hu, Jin, Winqvist, Ola, Rolny, Charlotte, Lundqvist, Andreas

Journal:

European Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 832 KB

english, 2013

7

Proteasome deubiquitinases as novel targets for cancer therapy

D’Arcy, Pádraig, Linder, Stig

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2012

Language:

english

File:

PDF, 658 KB

english, 2012

8

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

D'Arcy, Pádraig, Brnjic, Slavica, Olofsson, Maria Hägg, Fryknäs, Mårten, Lindsten, Kristina, De Cesare, Michelandrea, Perego, Paola, Sadeghi, Behnam, Hassan, Moustapha, Larsson, Rolf, Linder, Stig

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 754 KB

english, 2011

9

Piperlongumine induces inhibition of the ubiquitin–proteasome system in cancer cells

Jarvius, Malin, Fryknäs, Mårten, D’Arcy, Pädraig, Sun, Chao, Rickardson, Linda, Gullbo, Joachim, Haglund, Caroline, Nygren, Peter, Linder, Stig, Larsson, Rolf

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 734 KB

english, 2013

10

A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells

Sarhan, Dhifaf, Wennerberg, Erik, DâArcy, Padraig, Gurajada, Deepthy, Linder, Stig, Lundqvist, Andreas

Journal:

Cancer Immunology, Immunotherapy

Year:

2013

Language:

english

File:

PDF, 456 KB

english, 2013

11

Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

Felth, Jenny, Lesiak-Mieczkowska, Karolina, DâArcy, Padraig, Haglund, Caroline, Gullbo, Joachim, Larsson, Rolf, Linder, Stig, Bohlin, Lars, FryknÃ¤s, MÃ¥rten, Rickardson, Linda

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

12

Doxorubicin sensitizes human tumor cells to NK cell- and T-cell-mediated killing by augmented TRAIL receptor signaling

Wennerberg, Erik, Sarhan, Dhifaf, Carlsten, Mattias, Kaminskyy, Vitaliy O., D'Arcy, Padraig, Zhivotovsky, Boris, Childs, Richard, Lundqvist, Andreas

Journal:

International Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 524 KB

english, 2013

13

Induction of Tumor Cell Apoptosis by a Proteasome Deubiquitinase Inhibitor Is Associated with Oxidative Stress

Brnjic, Slavica, Mazurkiewicz, Magdalena, Fryknäs, Mårten, Sun, Chao, Zhang, Xiaonan, Larsson, Rolf, D'Arcy, Pádraig, Linder, Stig

Journal:

Antioxidants & Redox Signaling

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

14

Identification of an inhibitor of the ubiquitin–proteasome system that induces accumulation of polyubiquitinated proteins in the absence of blocking of proteasome function

Haglund, Caroline, Mohanty, Chitralekha, Fryknäs, Mårten, D'Arcy, Padraig, Larsson, Rolf, Linder, Stig, Rickardson, Linda

Journal:

Year:

2014

Language:

english

File:

PDF, 1.82 MB

english, 2014

15

Deubiquitinase inhibition as a cancer therapeutic strategy

D'Arcy, Padraig, Wang, Xin, Linder, Stig

Journal:

Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 2.67 MB

english, 2015

16

Note: Enhancement of the extreme ultraviolet emission from a potassium plasma by dual laser irradiation

Higashiguchi, Takeshi, Yamaguchi, Mami, Otsuka, Takamitsu, Nagata, Takeshi, Ohashi, Hayato, Li, Bowen, D’Arcy, Rebekah, Dunne, Padraig, O’Sullivan, Gerry

Journal:

Review of Scientific Instruments

Year:

2014

Language:

english

File:

PDF, 506 KB

english, 2014

17

Spectral and temporal behavior of an alkali metal plasma extreme ultraviolet source for surface morphology applications

Higashiguchi, Takeshi, Yamaguchi, Mami, Otsuka, Takamitsu, Terauchi, Hiromitsu, Yugami, Noboru, Yatagai, Toyohiko, D’Arcy, Rebekah, Dunne, Padraig, O’Sullivan, Gerry

Journal:

Applied Physics Letters

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

18

Characteristics of extreme ultraviolet emission from a discharge-produced potassium plasma for surface morphology application

Higashiguchi, Takeshi, Terauchi, Hiromitsu, Yugami, Noboru, Yatagai, Toyohiko, Sasaki, Wataru, D’Arcy, Rebekah, Dunne, Padraig, O’Sullivan, Gerry

Journal:

Applied Physics Letters

Year:

2010

Language:

english

File:

PDF, 447 KB

english, 2010

19

Microdischarge extreme ultraviolet source with alkali metal vapor for surface morphology application

Higashiguchi, Takeshi, Terauchi, Hiromitsu, Otsuka, Takamitsu, Yamaguchi, Mami, Kikuchi, Keisuke, Yugami, Noboru, Yatagai, Toyohiko, Sasaki, Wataru, D’Arcy, Rebekah, Dunne, Padraig, O’Sullivan, Gerry

Journal:

Journal of Applied Physics

Year:

2011

Language:

english

File:

PDF, 520 KB

english, 2011

20

Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15

Wang, Xin, D'Arcy, Pádraig, Caulfield, Thomas R., Paulus, Aneel, Chitta, Kasyapa, Mohanty, Chitralekha, Gullbo, Joachim, Chanan-Khan, Asher, Linder, Stig

Journal:

Chemical Biology & Drug Design

Year:

2015

Language:

english

File:

PDF, 2.15 MB

english, 2015

21

Spectroscopy of highly charged ions and its relevance to EUV and soft x-ray source development

O’Sullivan, Gerry, Li, Bowen, D’Arcy, Rebekah, Dunne, Padraig, Hayden, Paddy, Kilbane, Deirdre, McCormack, Tom, Ohashi, Hayato, O’Reilly, Fergal, Sheridan, Paul, Sokell, Emma, Suzuki, Chihiro, Higashi

Journal:

Journal of Physics B Atomic Molecular and Optical Physics

Year:

2015

Language:

english

File:

PDF, 2.87 MB

english, 2015

22

Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

Sarhan, Dhifaf, D'Arcy, Padraig, Lundqvist, Andreas

Journal:

International Journal of Molecular Sciences

Year:

2014

Language:

english

File:

PDF, 526 KB

english, 2014

23

Inhibition of proteasome deubiquitinase activity: a strategy to overcome resistance to conventional proteasome inhibitors?

Selvaraju, Karthik, Mazurkiewicz, Magdalena, Wang, Xin, Gullbo, Joachim, Linder, Stig, D’Arcy, Pádraig

Journal:

Drug Resistance Updates

Year:

2015

Language:

english

File:

PDF, 2.21 MB

english, 2015

24

SPIE Proceedings [SPIE SPIE Optical Engineering + Applications - San Diego, California (Sunday 21 August 2011)] Advances in X-Ray/EUV Optics and Components VI - Characterization of broadband emission around 40 nm from potassium plasma

Terauchi, Hiromitsu, Yamaguchi, Mami, Otsuka, Takamitsu, Higashiguchi, Takeshi, Yugami, Noboru, Yatagai, Toyohiko, D'Arcy, Rebekah M., Dunne, Padraig, O'Sullivan, Gerard, Morawe, Christian, Khounsary,

Year:

2011

Language:

english

File:

PDF, 405 KB

english, 2011

25

Multipotent Mesenchymal Stromal Cells Express FoxP3

Sundin, Mikael, DʼArcy, Pádraig, Johansson, C. Christian, Barrett, A. John, Lönnies, Helena, Sundberg, Berit, Nava, Silvia, Kiessling, Rolf, Mougiakakos, Dimitrios, Le Blanc, Katarina

Journal:

Journal of Immunotherapy

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

26

Iron chelators target both proliferating and quiescent cancer cells

Fryknäs, Mårten, Zhang, Xiaonan, Bremberg, Ulf, Senkowski, Wojciech, Olofsson, Maria Hägg, Brandt, Peter, Persson, Ingmar, D’Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Schughart, Leoni Kunz, Linde

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

27

Eradicating Quiescent Tumor Cells by Targeting Mitochondrial Bioenergetics

Zhang, Xiaonan, De Milito, Angelo, Demiroglu-Zergeroglu, Asuman, Gullbo, Joachim, D’Arcy, Padraig, Linder, Stig

Journal:

Trends in Cancer

Year:

2016

Language:

english

File:

PDF, 1.63 MB

english, 2016

28

Proteasome-associated deubiquitinases and cancer

Mofers, Arjan, Pellegrini, Paola, Linder, Stig, D’Arcy, Pádraig

Journal:

Cancer and Metastasis Reviews

Year:

2017

Language:

english

File:

PDF, 1.73 MB

english, 2017

29

Oncogenic Functions of the Cancer-Testis Antigen SSX on the Proliferation, Survival, and Signaling Pathways of Cancer Cells

D’Arcy, Padraig, Maruwge, Wessen, Wolahan, Barry, Ma, Limin, Brodin, Bertha, Pizzo, Salvatore V.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.42 MB

english, 2014

30

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors

Zhang, Xiaonan, de Milito, Angelo, Olofsson, Maria, Gullbo, Joachim, D’Arcy, Padraig, Linder, Stig

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

31

The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage

Zhang, Xiaonan, Pellegrini, Paola, Saei, Amir Ata, Hillert, Ellin-Kristina, Mazurkiewicz, Magdalena, Olofsson, Maria Hägg, Zubarev, Roman A., D'Arcy, Pádraig, Linder, Stig

Journal:

Biochemical Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

32

A drug screening assay on cancer cells chronically adapted to acidosis

Pellegrini, Paola, Serviss, Jason T., Lundbäck, Thomas, Bancaro, Nicolo, Mazurkiewicz, Magdalena, Kolosenko, Iryna, Yu, Di, Haraldsson, Martin, D’Arcy, Padraig, Linder, Stig, De Milito, Angelo

Journal:

Cancer Cell International

Year:

2018

Language:

english

File:

PDF, 4.35 MB

english, 2018

33

Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation

Hillert, Ellin-Kristina, Brnjic, Slavica, Zhang, Xiaonan, Mazurkiewicz, Magdalena, Saei, Amir Ata, Mofers, Arjan, Selvaraju, Karthik, Zubarev, Roman, Linder, Stig, D’Arcy, Padraig

Journal:

Year:

2019

File:

PDF, 19.97 MB

2019

34

Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation

Hillert, Ellin-Kristina, Brnjic, Slavica, Zhang, Xiaonan, Mazurkiewicz, Magdalena, Saei, Amir Ata, Mofers, Arjan, Selvaraju, Karthik, Zubarev, Roman, Linder, Stig, D’Arcy, Padraig

Journal:

Year:

2019

Language:

english

File:

PDF, 19.97 MB

english, 2019

35

Repurposing of auranofin: thioredoxin reductase remains a primary target of the drug

Zhang, Xiaonan, Selvaraju, Karthik, Saei, Amir Ata, D'Arcy, Padraig, Zubarev, Roman A., Arnér, Elias SJ., Linder, Stig

Journal:

Year:

2019

Language:

english

File:

PDF, 3.06 MB

english, 2019

36

Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment

Zhang, Xiaonan, Espinosa, Belén, Saei, Amir Ata, D'Arcy, Padraig, Zubarev, Roman A., Linder, Stig

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2019

Language:

english

File:

PDF, 9.20 MB

english, 2019

37

Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19

Clemente, Valentino, DâArcy, Padraig, Bazzaro, Martina

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 950 KB

2020

38

Identification of proteasome inhibitors using analysis of gene expression profiles

Mofers, Arjan, Selvaraju, Karthik, Gubat, Johannes, D'Arcy, Padraig, Linder, Stig

Journal:

European Journal of Pharmacology

Year:

2020

File:

PDF, 36.22 MB

2020